Neutrophil Oxidative Burst
Order Name
NOB
Test Number: None
Revision Date 03/20/2023
Test Number: None
Revision Date 03/20/2023
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Neutrophil Oxidative Burst
|
Flow cytometry |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 5mL | Whole Blood | Sodium Heparin (Green Top / No-Gel) | Room Temperature |
| Instructions | Order using the MISC test Collect whole blood, green (Sodium Heparin) tube. Send a whole blood Sodium Heparin in the original tube Collect Monday through Wednesday Specimens must be collected after 9am and received in the lab by 3pm Notify lab personnel prior to collection, Dr. Miller at 918-409-6645 or Sonya Bruening at 918-791-8326 Stability: Room temperature - 24 hours; Frozen-Unacceptable |
|||
| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Collect Monday through Wednesday |
| Expected TAT | 2-3 business days |
| Clinical Use | Patients with chronic granulomatous disease (CGD) have an inherited primary immunodeficiency with recurrent infections and granulomas. Their neutrophils are fully capable of ingesting bacteria and fungi but cannot kill because of the dysfunction of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system and thus an inability to produce superoxide anions required for killing of the bacteria and fungal organisms. The DHR flow assay provides an assessment of the reactive oxygen intermediate (ROI) production by measuring the NADPH oxidase activity. |
| Notes | Labcorp test code: 805245 Testing referred to Eurofins Viracor This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration |
| CPT Code(s) | 82657 |
| Lab Section | Reference Lab |